Peptide Database

Peptide NameCorticotropin-releasing factor

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Stress-related neuropeptide

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC204H327N59O64S2

DescriptionStandard

        SEEPPISLDLTFHLLRELEMARAEQLAQQAHSNRKLMENF
    

Molecular Weight4694.27 Da

Isoelectric Point (pI)5.09

Net Charge (pH 7.0)-3.35

Net Charge (pH 7.4) -3.67

Charge Density (pH 7.0) -0.0837

GRAVY Index-0.61

Hydrophobic Moment 0.55

Boman Index-0.12

Instability Index44.96

Aliphatic Index 88.00

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2007.19

LogP -18.82

H-bond Donors 67.0

H-bond Acceptors 65.0

Rotatable Bonds 160.0

Heavy Atoms 329.0

Ring Count 6.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0031193 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilySauvagine/corticotropin-releasing factor/urotensin I

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Stress-related neuropeptide

RECORD: Rec_0257803 VERIFIED: YES