Peptide Database

Peptide NameSecretogranin-1

Function Ontology

Hormonal / Endocrine ▸ Secretory pathway peptide ▸ Secretory granule peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length648 amino acids

Chemical FormulaC3079H4759N973O1057S5

DescriptionStandard

        MPVDNRNHNEEMVAHCIIEVLSNALSKSNAPPITPECRQVLKKGGKEVKDEEKGANENTRFEVRLLRDPADTSETQRPSGGREGAEAPSEDTQGPPGADVEGGGHSREGAGKPRGGPYSSDNPVAKEGKTRHSEKSEGQDREEEEGEKYQKRERGEEGSEERHLQEPGETQTAFLNQGNRATAKKKEEFESRYDAHSAGGPAKTHSRERSSQESGEETGSQDAAPGEPESPPEGQEAPEESQEDASLEVDKRRWRPRHHHGRSRPDRAPQEGSPPPEERGHPREESEESVLGLASPGGQRTRHPTHYPASEEEAEHGEEVRSSSSVQAPGDLVGARYGGRGGAEHRAARRPGEESPEQDRRVGASSELRNKGPGHSEESEEERGDEGQRHHRAWAGGPRADAPPDPAEEEQFWGEAHRPVPESQVDEARRHPQAKLRNYLNRGEENGEEGAPGRWQQPEDLQGPGEHAAEARLPGKPYAAHRIPEKKRLGELLNPYYVPPQWESSHFERKDNVGDNFLEGEDANGVTLNEKTFFPEYSYDWWEKKPFEEDVNWGYEERNLAPKLDLKRQYDRVAELDQLLHYRKKSAEFPDFYDSGEHLSPRHAAESEKERAGQGVLTEEEEKELENLAAMDLELQKIAEKFSGNRRG
    

Molecular Weight72477.94 Da

Isoelectric Point (pI)5.09

Net Charge (pH 7.0)-43.96

Net Charge (pH 7.4) -45.80

Charge Density (pH 7.0) -0.0678

GRAVY Index-1.48

Hydrophobic Moment 0.73

Boman Index-0.32

Instability Index69.72

Aliphatic Index 41.05

Aromaticity 0.0540

Extinction Coeff. Reduced 66350.00

Extinction Coeff. Oxidized 66475.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0318480 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyChromogranin/secretogranin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsThr59 Phosphothreonine; Thr72 Phosphothreonine; Ser79 Phosphoserine; Lys129 Acetylation; Tyr149 Sulfotyrosine; Ser159 Phosphoserine; Ser286 Phosphoserine; Ser310 Phosphoserine; Ser355 Phosphoserine; Ser376 Phosphoserine; Ser379 Phosphoserine; Tyr439 Sulfotyrosine; Ser504 Phosphoserine; Ser505 Phosphoserine; Tyr537 Sulfotyrosine; Tyr539 Sulfotyrosine; Ser586 Phosphoserine; Tyr593 Sulfotyrosine; Ser595 Phosphoserine; Ser600 Phosphoserine

Bio-Activity Profile

Function

Secretory granule peptide Neuropeptide precursor