Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC461H752N112O114S2

DescriptionStandard

        MTIQKRVTQCFITLLIVILIGLLFSGTLPSVSLAAQFGISHVAAVQIIEIASGTGSIWAIIAIVGGSFGWGVVILAAAKILIKKYGKKQAAVW
    

Molecular Weight9751.71 Da

Isoelectric Point (pI)10.14

Net Charge (pH 7.0)5.57

Net Charge (pH 7.4) 5.28

Charge Density (pH 7.0) 0.0599

GRAVY Index1.19

Hydrophobic Moment 0.60

Boman Index0.47

Instability Index19.32

Aliphatic Index 145.81

Aromaticity 0.0860

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3541.54

LogP -21.07

H-bond Donors 126.0

H-bond Acceptors 123.0

Rotatable Bonds 323.0

Heavy Atoms 689.0

Ring Count 13.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0220176 VERIFIED: NO

Provenance & Taxonomy

OrganismBrochothrix campestris FSL F6-1037 [Bacterium]

FamilyBacteriocin

Tax ID1265861

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal