Peptide Database

Peptide NameMolt-inhibiting hormone

Function Ontology

Developmental biology ▸ Molting regulation

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC398H616N116O121S7

DescriptionStandard

        RVINDECPNLIGNRDLYKKVEWICEDCSNIFRKTGMASLCRRNCFFNEDFVWCVHATERSEELRDLEEWVGILGAGRD
    

Molecular Weight9186.31 Da

Isoelectric Point (pI)4.96

Net Charge (pH 7.0)-4.18

Net Charge (pH 7.4) -4.55

Charge Density (pH 7.0) -0.0536

GRAVY Index-0.46

Hydrophobic Moment 0.68

Boman Index-0.12

Instability Index49.15

Aliphatic Index 77.44

Aromaticity 0.1026

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 18365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3883.96

LogP -36.26

H-bond Donors 142.0

H-bond Acceptors 125.0

Rotatable Bonds 308.0

Heavy Atoms 642.0

Ring Count 13.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0327438 VERIFIED: YES

Provenance & Taxonomy

OrganismCarcinus maenas [Animal]

FamilyArthropod CHH/MIH/GIH/VIH hormone

Tax ID6759

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Arthropod neurohormone

RECORD: Rec_0347816 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0421427 VERIFIED: YES

Provenance & Taxonomy

OrganismCarcinus maenas [Animal]

FamilyMolt-inhibiting hormone

Tax ID6759

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-44; 24-40; 27-53

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Molting regulator

Half-LifeMammalian: 1 hour; Yeast: 2 min; E. coli: 2 min