Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length419 amino acids

Chemical FormulaC2111H3304N544O607S16

DescriptionStandard

        MRRESLLVLGICWFLSSSEGVNPGFAGRITKKGLDYACQEGVATLQKDLPAITLPEFSGSYRVKMIGNVNYRFYSLNIRRFELFHSTIEPMPGQGLRVSVSNALAEMTGHWELKKRWLKDDGSFELKLDGISISVGLKLGSDDTGRPTVTTLDCTTHISNVDIDISGKWEWLYNLFERKIESSFKAVMESKICEMVRISVNSKLQSHLQSLPITANIDHTSSIDYSLVGPPVATSQCVDLDLKGEFFSTAHRSPAPFPAPPLSFPLDPNRMVQFGISTYFFNTAGDVYYKSGSLTFWIVDEMVPPEVKIRLNTSSFQPFIPQLKKLYPNMAMKLKVSPSSVPSLSISPETLSLTPSVDIQAFAVLPDSSLAPLFVIGATSPVSAKIDVNSTRIFGNLKLGRLKFSLKHSDVGFFTVRWM
    

Molecular Weight46529.14 Da

Isoelectric Point (pI)8.65

Net Charge (pH 7.0)4.10

Net Charge (pH 7.4) 3.36

Charge Density (pH 7.0) 0.0098

GRAVY Index-0.02

Hydrophobic Moment 0.65

Boman Index0.10

Instability Index46.41

Aliphatic Index 90.45

Aromaticity 0.1002

Extinction Coeff. Reduced 53400.00

Extinction Coeff. Oxidized 53650.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0009475 VERIFIED: NO

Provenance & Taxonomy

OrganismNotechis scutatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria