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MYP_100759
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Basic Information
Beta-casomorphin-7
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid receptor ligand
Regulatory peptide ▸ Stimulation activity
Wound healing/Regeneration ▸ Wound healing
Standard
30 amino acids
C156H242N38O44S2
Standard
Sequence
GVSKVKEAMAPKHKEMPFPKYPVEPFTESQ
Physicochemical Analysis
3417.95 Da
8.34
0.85
0.58
0.0284
-0.89
0.41
-0.09
94.42
35.67
0.1000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1295.26
-9.73
41.0
48.0
109.0
240.0
9.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0021574 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casomorphin
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid receptor ligand Mucin secretagogue
HT29-MTX cells
Mucin secretion assay
PaperA novel bioactive peptide from yoghurts modulates expression of the gel-forming MUC2 mucin as well as population of goblet cells and Paneth cells along the small intestine | Plaisancie, P. et al. | DOI: 10.1016/j.jnutbio.2012.05.004 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0068948 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Stimulatory
PaperPlaisanci¨¦ P., Claustre J., Estienne M., Henry G., Boutrou R., Paquet A., L¨¦onil J.. A novel bioactive peptide from yoghurts modulates expression of the gel-forming MUC2 mucin as well as population of goblet cells and Paneth cells along the small intestine. J. Nutr. Biochem., 24, 213-221, 2013 24 213-221.
RECORD: Rec_0094005 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casofensin
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Wound healing Cell-proliferative
Rats
100 μM
Cell proliferation assay
PaperProtective effects of β-casofensin, a bioactive peptide from bovine β-casein, against indomethacin-induced intestinal lesions in rats | Bessette, C. et al. | DOI: 10.1002/mnfr.201500680 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0180867 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casomorphin
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Mucin secretagogue Gastroprotective
HT29-MTX cells
Mucin secretion assay
PaperA novel bioactive peptide from yoghurts modulates expression of the gel-forming MUC2 mucin as well as population of goblet cells and Paneth cells along the small intestine | Plaisancie, P. et al. | DOI: 10.1016/j.jnutbio.2012.05.004 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0359667 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Mucin secretagogue Gastroprotective
HT29-MTX cells
Paperβ-Casein(94-123)-derived peptides differently modulate production of mucins in intestinal goblet cells | Plaisancie, P. et al. | DOI: 10.1017/S0022029914000533 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry