Peptide Database

Peptide NameDPV10

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC63H113N31O18

DescriptionStandard

        SRRARRSPRHLGSG
    

Molecular Weight1592.77 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)4.55

Net Charge (pH 7.4) 4.29

Charge Density (pH 7.0) 0.3248

GRAVY Index-1.78

Hydrophobic Moment 0.87

Boman Index-0.77

Instability Index176.01

Aliphatic Index 35.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 831.70

LogP -13.21

H-bond Donors 33.0

H-bond Acceptors 24.0

Rotatable Bonds 53.0

Heavy Atoms 112.0

Ring Count 2.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0101458 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetNot available

RECORD: Rec_0127243 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

RECORD: Rec_0144839 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDPV/CAP37-derived

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition for conjugation

C-TermNone

Other ModsN-term detail: Cys added to N -terminus for conjugation of report

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetHeLa; HCT116; HL-60; K562; Molt4; NIH-3T3; primary hepatocyte cultures

MethodCellular uptake assay

RECORD: Rec_0276339 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

RECORD: Rec_0385503 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDPV

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCysteine addition

C-TermNone

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery