Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC433H696N118O115S10

DescriptionStandard

        MKMLCIFLTFVFIVSCGPSVPQKKTREVAERKRECQLVRGACKSECNTWEYVHYYCDVKPCCVVRDYQKPIINKITTKLYRK
    

Molecular Weight9715.53 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)8.51

Net Charge (pH 7.4) 8.09

Charge Density (pH 7.0) 0.1038

GRAVY Index-0.25

Hydrophobic Moment 0.72

Boman Index-0.10

Instability Index45.82

Aliphatic Index 77.07

Aromaticity 0.1098

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3800.87

LogP -30.01

H-bond Donors 142.0

H-bond Acceptors 135.0

Rotatable Bonds 324.0

Heavy Atoms 676.0

Ring Count 15.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0351738 VERIFIED: NO

Provenance & Taxonomy

OrganismMandrillus leucophaeus [Animal]

FamilyDefensin

Tax ID9568

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence