Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC476H758N118O135S9

DescriptionStandard

        MKLFLVLIFLLFEVPSDVAWQKKCFNNVQGYCRKKCNMGEIYDVSCQGGKLCCVNEAENKKYLAVPVASKAPEVVDQNMDYIVLPTTTVVTVQL
    

Molecular Weight10582.40 Da

Isoelectric Point (pI)7.52

Net Charge (pH 7.0)0.45

Net Charge (pH 7.4) 0.11

Charge Density (pH 7.0) 0.0047

GRAVY Index0.20

Hydrophobic Moment 0.54

Boman Index0.12

Instability Index26.48

Aliphatic Index 98.30

Aromaticity 0.0957

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4078.55

LogP -32.08

H-bond Donors 141.0

H-bond Acceptors 145.0

Rotatable Bonds 351.0

Heavy Atoms 738.0

Ring Count 14.0

Amide Bonds 104.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056545 VERIFIED: NO

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic