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MYP_100561
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Basic Information
P9
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
20 amino acids
C116H199N37O28
Standard
Sequence
SYERKINRHFKTLKKNLKKK
Physicochemical Analysis
2560.05 Da
10.79
7.54
7.27
0.3771
-1.90
0.84
-0.68
-10.07
58.50
0.1000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1135.01
-9.68
41.0
37.0
96.0
181.0
3.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0062488 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Candida albicans ATCC 5314
64 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0140580 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Murine blood [HC10 = >640 microg/mL, HC50 = >640 microg/mL, Percent Hemolysis ± SD Hmax (100%) = 7.06 ± 3.7]
640 μg/mL
HC50
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0148999 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
S. mutans ATCC UA159
64 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0223231 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
S. sangui ATCC 10556
64 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0309799 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
MRSA 18466
16 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
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