Peptide Database

Peptide NameAnnexin A1 biomimetic short peptide (ANXA1sp)

Function Ontology

Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging

Standard StatusStandard

Sequence Length3 amino acids

Chemical FormulaC19H25N5O5

DescriptionStandard

QAW

Molecular Weight403.43 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0800

GRAVY Index-0.87

Hydrophobic Moment 0.58

Boman Index0.19

Instability Index6.67

Aliphatic Index 33.33

Aromaticity 0.3333

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 180.40

LogP -0.62

H-bond Donors 6.0

H-bond Acceptors 5.0

Rotatable Bonds 10.0

Heavy Atoms 29.0

Ring Count 2.0

Amide Bonds 3.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0020387 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyTripeptide

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

Bio-Activity Profile

Function

Cardioprotective Cytoprotective Anti-apoptotic SIRT3 activation Anti-aging

Targetmale Sprague-Dawley rats; myocardium; cardiopulmonary bypass/cardioplegic arrest/deep hypothermic circulatory arrest

MethodELISA; Western blot; TUNEL; cardiac function assessment

RECORD: Rec_0252342 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyTripeptide

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

Bio-Activity Profile

Function

Cardioprotective Cytoprotective Anti-apoptotic SIRT3 activation Anti-aging

Targetadult rat ventricular cardiomyocytes; oxygen-glucose deprivation/reoxygenation

MethodELISA; cell viability assay; apoptosis assay; Western blot

RECORD: Rec_0279748 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyTripeptide

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

Bio-Activity Profile

Function

Cardioprotective Cytoprotective Anti-apoptotic SIRT3 activation Anti-aging

Targetadult rat ventricular cardiomyocytes; oxygen-glucose deprivation/reoxygenation

MethodELISA; cell viability assay; apoptosis assay; Western blot