MYP_100485
Dermaseptin t-DPH1 [S4K,A11A,L18K]
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
▸
Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Antimicrobial
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Antifungal
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
▸
General toxin
▸
Cytotoxic
Standard
21 amino acids
C98H171N29O23
Standard
GLWKKIKNVAKAAGKAAKGAL
2123.59 Da
10.70
5.75
5.54
0.2740
-0.09
0.68
0.04
0.59
98.10
0.0476
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
860.32
-6.72
30.0
29.0
76.0
150.0
2.0
21.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0292447
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
Klebsiella pneumoniae ATCC 43816
4 μM
MIC
RECORD: Rec_0299035
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
Candida albicans ATCC 10231
64 μM
MIC
RECORD: Rec_0311154
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse RBC [HC50= 834.6 μM]
834.6 μM
HC50
RECORD: Rec_0318013
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
Methicillin-resistant Staphylococcus aureus
32 μM
MIC
RECORD: Rec_0351564
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Anticancer
Cytotoxic
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