Peptide Database

Peptide NameCCL11

Function Ontology

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC376H627N107O102S5

DescriptionStandard

        HPGSIPTSCCFIMTSKKIPNTLLKSYKRITNNRCTLKAIVFKTRLGKEICADPKKKWVQDATKHLDQKLQTPKP
    

Molecular Weight8438.98 Da

Isoelectric Point (pI)10.04

Net Charge (pH 7.0)11.89

Net Charge (pH 7.4) 11.50

Charge Density (pH 7.0) 0.1606

GRAVY Index-0.62

Hydrophobic Moment 0.68

Boman Index-0.16

Instability Index15.73

Aliphatic Index 75.14

Aromaticity 0.0541

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3402.72

LogP -33.23

H-bond Donors 121.0

H-bond Acceptors 121.0

Rotatable Bonds 286.0

Heavy Atoms 590.0

Ring Count 13.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012789 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsO-linked glycoslylation of residue 71 and disulphide bond formation between cysteine residues at postions 9 and 34, and 10 and 50

Bio-Activity Profile

Function

Receptor agonist Chemotactic Immunomodulatory Signaling peptide

TargetCCR3 (Human); CCR2 (Mouse); CCR3 (Mouse)