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MYP_100437
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Basic Information
Cathelin-related peptide SC5
Anticancer
Anticancer ▸ Anti-proliferative
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Antiviral
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
29 amino acids
C146H260N52O32
Standard
Sequence
RGLRRLGRKIAHGVKKYGPTVLRIIRIAG
Physicochemical Analysis
3255.96 Da
12.00
8.84
8.58
0.3049
-0.21
1.07
-0.18
26.41
121.03
0.0345
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1387.93
-11.43
53.0
42.0
113.0
230.0
3.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0129797 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Cathelicidin
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 25923
5 - 10 μg/mL
MIC
PMID8549789 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8549789/
RECORD: Rec_0142880 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
9940
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa MR3007
0.18 μM
MIC
PMID8549789;11932493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8549789/
RECORD: Rec_0152258 VERIFIED: NO
Provenance & Taxonomy
Ovis aries [Animal]
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer Anti-proliferative
PaperPatent US 7071293 B1 Evidence URLhttps://patents.google.com/patent/US7071293B1/en PatentUS 7071293 B1
RECORD: Rec_0175710 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Cathelicidin
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Bacillus megaterium Bm11
0.25 μM
MIC
PapercDNA sequences of three sheep myeloid cathelicidins
RECORD: Rec_0178400 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Cathelicidin
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Refer pmid-10768969[ Pseudomonas aeruginosa PAO1 (
1.24 μM
MIC
PMID8549789 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8549789/
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