Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length478 amino acids

Chemical FormulaC2377H3752N606O694S18

DescriptionStandard

        MLPSVVVLLMFISGTCAENPAIQFVLTNKGLQKGKHRVTDWIQQHLENVTLPDISSDIHIPILGNIHYTLTDISITKCDLPEPSVEFYPNVTGFKTSISGLSVALTGEWETHYHIIHDGGSLDMAVFDLNVISAVELGKDAGGHLSVSSISCDAQVGDVDVRFHGGDSWIFQPFVKYFKRQIIGKIQKSICPSVEEMIVTLESHLQAMNVSFDVNQLLSLDLNLTSVPVVDATSLNLGLKGEFYNIRTHSEPPFKLKSFTLPEQQGYMVSVGLSEFTLNSASYGYYSAGLLQADINDSMILQHLHMHLNTSVVGLLIPQLLSMFPGLPMSLKVYARQVPVFSFQHDVVKLGLHGAVKAFAIQPNGTQIPLFTLNVDSDLSGKIYVSDGKLKGSVKMDKFTLKLAASEVGTFKTDTLENLTRCGIQTIVFPKVNEKLDKGFVLPRIKQAQLVNSVLKVEQGFMAMSSDVEVFPSDKGLK
    

Molecular Weight52500.03 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-8.11

Net Charge (pH 7.4) -9.32

Charge Density (pH 7.0) -0.0170

GRAVY Index0.13

Hydrophobic Moment 0.80

Boman Index0.16

Instability Index34.98

Aliphatic Index 103.08

Aromaticity 0.0816

Extinction Coeff. Reduced 32890.00

Extinction Coeff. Oxidized 33140.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0218976 VERIFIED: NO

Provenance & Taxonomy

OrganismAnabas testudineus (Climbing perch) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria