Peptide Database

Peptide NameI33

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC183H291N49O44S

DescriptionStandard

        QLLIRMIYKNILFYLVPGPGHGAEPERRNIKYL
    

Molecular Weight3913.63 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)2.85

Net Charge (pH 7.4) 2.58

Charge Density (pH 7.0) 0.0863

GRAVY Index-0.13

Hydrophobic Moment 0.62

Boman Index0.06

Instability Index81.79

Aliphatic Index 118.18

Aromaticity 0.1212

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1499.13

LogP -6.98

H-bond Donors 51.0

H-bond Acceptors 49.0

Rotatable Bonds 127.0

Heavy Atoms 277.0

Ring Count 8.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0360416 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHIV-1:Inhibition of 3′-end processing catalyzed by integrase

Activity9 μM

MethodIC50

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