Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC411H644N122O106S8

DescriptionStandard

        MALSRKAVSLVFAFLFILAQFPLGGQAGLEYSQPFPGGEFVACKPCRLGRGRCRRYCHEDEKADGNCRLNFFCCRPRIQKAK
    

Molecular Weight9246.78 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)7.52

Net Charge (pH 7.4) 7.14

Charge Density (pH 7.0) 0.0918

GRAVY Index-0.16

Hydrophobic Moment 0.56

Boman Index-0.05

Instability Index41.04

Aliphatic Index 67.93

Aromaticity 0.1220

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3675.84

LogP -33.88

H-bond Donors 135.0

H-bond Acceptors 123.0

Rotatable Bonds 304.0

Heavy Atoms 647.0

Ring Count 16.0

Amide Bonds 87.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0240485 VERIFIED: NO

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic