Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length107 amino acids

Chemical FormulaC520H841N145O158S15

DescriptionStandard

        MSVMKPCLMKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPNDQKCCLKLSVKITSSKNVKEDYDCNSNLSVTNSSSYSHI
    

Molecular Weight12133.09 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)4.59

Net Charge (pH 7.4) 4.11

Charge Density (pH 7.0) 0.0429

GRAVY Index-0.35

Hydrophobic Moment 0.61

Boman Index-0.05

Instability Index44.56

Aliphatic Index 71.96

Aromaticity 0.0654

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4910.65

LogP -53.86

H-bond Donors 177.0

H-bond Acceptors 180.0

Rotatable Bonds 406.0

Heavy Atoms 838.0

Ring Count 16.0

Amide Bonds 118.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0148656 VERIFIED: NO

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyDefensin

Tax ID9595

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence