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MYP_100302
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Basic Information
CP-2
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Therapeutic / Biomedical activity ▸ Protective bioactivity ▸ Cell protection ▸ Cytoprotection
Standard
37 amino acids
C216H324N52O61
Standard
Sequence
KEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYVW
Physicochemical Analysis
4625.19 Da
4.77
-2.23
-2.45
-0.0603
-0.78
0.69
-0.06
27.88
102.70
0.1622
20970.00
20970.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1872.95
-9.09
63.0
59.0
154.0
329.0
10.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001938 VERIFIED: YES
Provenance & Taxonomy
Severe acute respiratory syndrome-related coronavirus [Virus]
Virus-derived peptide
694009;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Fusion inhibitor Cytoprotective
SARS coronavirus (Fusion); Vero E6
Cytopathic effect
PaperInteraction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and identification of fusion inhibitors. | Liu S, Xiao G, Chen Y, He Y, Niu J, Escalante CR, Xiong H, Farmar J, Debnath AK, Tien P, Jiang S. | Lancet. 2004 | PMID:15043961 PMID15043961 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15043961/
RECORD: Rec_0061456 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
SARS-CoV-2
PMID34591335 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34591335/
RECORD: Rec_0108214 VERIFIED: YES
Provenance & Taxonomy
Severe acute respiratory syndrome-related coronavirus [Virus]
HR2-derived fusion inhibitor
694009
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus
19 μM
IC50
PaperInteraction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and identification of fusion inhibitors PMID15043961 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15043961/
RECORD: Rec_0163300 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/