MYP_100301
Omega-conotoxin GVIA
Annotation / Sequence feature
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Nuclear export signal
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Membrane / Ion-channel modulation
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Ion channel inhibition
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Venom / Toxin
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General toxin
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Toxic
Venom / Toxin
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General toxin
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Toxin
Venom / Toxin
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Toxin
Standard
27 amino acids
C120H187N37O41S6
Standard
CKSPGSSCSPTSYNCCRSCNPYTKRCY
2996.38 Da
8.90
3.70
3.40
0.1369
-0.89
0.51
-0.28
96.53
0.00
0.1111
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1278.10
-21.17
52.0
51.0
90.0
204.0
6.0
28.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0244157
VERIFIED: YES
Provenance & Taxonomy
Conus geographus [Animal]
conotoxin O1 superfamily
6490; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
1-16; 8-19; 15-26
4-Pro: 4-hydroxyproline; 10-Pro: 4-hydroxyproline; 21-Pro: 4-hydroxyproline
Bio-Activity Profile
Toxin
Venom
conotoxin O1 superfamily
Ion channel inhibitor
Pathogenesis-associated
Conotoxin
RECORD: Rec_0425573
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 59.3%, C 40.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic
Cytotoxic