Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length472 amino acids

Chemical FormulaC2323H3724N588O669S19

DescriptionStandard

        MFLCCWLGLVALIPTTLSTNPGVKVRLTEKGIEYGRQLGMAVIQQKLRSIKIPDFSGTETVSPIGKVQYSLSNMHIVNVGLPKSSVDLVPGTGVTLSIGDAFISLNGNWRVKYLRIIKDSGSFDLNVNGLSIATTISIKSDETGRPAVSTASCSATVGSAKVKFHGGASWLYNLFTTFIDKALRNALQKQICPLVADAVSDLNPQLKTLNVLAKVDKYAEIEYSMVSSPTVLKSSIDLSLKGEFYNIGKHQEPPFSPAAFYLPPQNNNMLYIGMSAFTVNSAAFVYNNAGVLSLSVTDDMIPKSSPIRLNTKTFGAFIPQIAKQFPGLMMKLLMKMEKIPTLTFEPNNATVQATTTVTAFAIQTNSTLSPLFVLNLEASVSARMFVSEMKLAAAVTLNKMDLTLAKSYVGDFQVGPLENVFQGVLKWVVIPTVNVQLAKGYPLPTIGKMKLVNTQLNVLKDYILIGTDVQFS
    

Molecular Weight51203.19 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)11.73

Net Charge (pH 7.4) 11.20

Charge Density (pH 7.0) 0.0249

GRAVY Index0.21

Hydrophobic Moment 0.72

Boman Index0.17

Instability Index31.18

Aliphatic Index 102.20

Aromaticity 0.0826

Extinction Coeff. Reduced 41370.00

Extinction Coeff. Oxidized 41620.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0078376 VERIFIED: NO

Provenance & Taxonomy

OrganismOreochromis niloticus (Not founde tilapia) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria