Peptide Database

Peptide NameProphenin-2 (C12) (PF-2) (PR-2) (Prophenin-1-like)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length228 amino acids

Chemical FormulaC1200H1815N331O299S6

DescriptionStandard

        METQRASLCLGRWSLWLLLLALVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTRRPPELCDFKENGRVKQCVGTVTLDQIKDPLDITCNEGVRRFPWWWPFLRRPRLRRQAFPPPNVPGPRFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPPFPPPIFPGPWFPPPPPFRPPPFGPPRFPGRR
    

Molecular Weight25854.68 Da

Isoelectric Point (pI)10.56

Net Charge (pH 7.0)12.48

Net Charge (pH 7.4) 12.16

Charge Density (pH 7.0) 0.0547

GRAVY Index-0.63

Hydrophobic Moment 0.77

Boman Index-0.06

Instability Index68.54

Aliphatic Index 60.26

Aromaticity 0.1140

Extinction Coeff. Reduced 35980.00

Extinction Coeff. Oxidized 36230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0398032 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyCathelicidin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria