Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC337H532N94O89S10

DescriptionStandard

        MRMLLFLFAVFFFLAPAKNEFFDERCNKLHGKCMRTCYKNEEIVALCGSSKRCCLKLQPCGRNSGE
    

Molecular Weight7645.06 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)4.53

Net Charge (pH 7.4) 4.14

Charge Density (pH 7.0) 0.0687

GRAVY Index-0.05

Hydrophobic Moment 0.60

Boman Index-0.03

Instability Index41.87

Aliphatic Index 68.03

Aromaticity 0.1212

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2971.94

LogP -25.35

H-bond Donors 110.0

H-bond Acceptors 105.0

Rotatable Bonds 259.0

Heavy Atoms 530.0

Ring Count 11.0

Amide Bonds 70.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0183598 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyDefensin

Tax ID9986

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence