Peptide Database

Peptide NameRanatuerin-2PRa

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC131H229N37O36S3

DescriptionStandard

        GLMDVFKGAAKNLLASALDKIRCKVTKC
    

Molecular Weight2994.64 Da

Isoelectric Point (pI)9.59

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.1335

GRAVY Index0.29

Hydrophobic Moment 0.57

Boman Index0.03

Instability Index-13.92

Aliphatic Index 104.64

Aromaticity 0.0357

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1199.17

LogP -10.67

H-bond Donors 44.0

H-bond Acceptors 43.0

Rotatable Bonds 106.0

Heavy Atoms 207.0

Ring Count 1.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0391112 VERIFIED: NO

Provenance & Taxonomy

OrganismRana pirica [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide23-28

Bio-Activity Profile

Function

Antimicrobial Antibacterial Hemolytic

TargetEscherichia coli, Pseudomonas aeruginosa, Enterobacter cloacae, Klebsiella pneumoniae, Staphylococcus aureus

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