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MYP_100218
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Anti-Influenza virus
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza
Antiviral ▸ Anti-Paramyxovirus ▸ Anti-HPIV cross
Antiviral ▸ Anti-Paramyxovirus ▸ Anti-HPIV ▸ Anti-HPIV3 cross
Antiviral ▸ Anti-Pneumovirus ▸ Anti-RSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Therapeutic / Biomedical activity ▸ Protective bioactivity ▸ Cell protection ▸ Cytoprotection
Standard
35 amino acids
C177H284N54O60
Standard
Sequence
IELNKAKSDLEESKEWIRRSNQKLDSIGNWHQSST
Physicochemical Analysis
4128.47 Da
6.78
-0.14
-0.41
-0.0041
-1.35
0.66
-0.32
88.83
69.71
0.0571
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1921.72
-22.83
67.0
61.0
146.0
291.0
5.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0048457 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Evidence URLhttps://patents.google.com/patent/US6228983B1/en PatentUS 6228983 B1
RECORD: Rec_0085988 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
HIV gp41 fusion inhibitor
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-HIV Anti-Influenza Anti-HPIV3
Human parainfluenza virus 3
PaperLong-lasting antiviral fusion inhibitor peptide conjugates comprising albumin and human immunodeficiency virus (HIV) peptides Evidence URLhttps://patents.google.com/patent/US7582301B1/en PatentUS 7582301 B1
RECORD: Rec_0107503 VERIFIED: YES
Provenance & Taxonomy
Human parainfluenza virus 3 [Virus]
Virus-derived peptide
11216;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Fusion inhibitor
Human parainfluenza virus type 3 (Hemagglutinin-Neuraminidase)
Cell-fusion assay
PaperMethods and compositions for inhibition of membrane fusion-associated events | Shawn O'Lin, Dennis Michael, Stephen Robert | Trimeris, Inc., Durham NC (US) | Patent:US6951717 Evidence URLhttps://patents.google.com/patent/US6951717/en PatentUS6951717
RECORD: Rec_0209423 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 48.6%, E 0.0%, T 25.7%, C 25.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0220186 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Respiratory syncytial virus fusion-inhibitory peptide
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-Influenza Anti-RSV Anti-HPIV3 Fusion inhibitor
Human parainfluenza virus 3
PaperHuman respiratory syncytial virus peptides with antifusogenic and antiviral activities Evidence URLhttps://patents.google.com/patent/US6228983B1/en PatentUS 6228983 B1
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