Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC546H874N146O169S3

DescriptionStandard

        PDLSGYEKFGLGNVKYNISRIHVTAVEFPSASISLIPGTGIKLVIGNASLTIDMNWNIRTWMFKDSGRSTVYISKVSVTAIFSTPLDNTGHTSISLSSCRTTSGDIDIKLNGKS
    

Molecular Weight12283.85 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)3.13

Net Charge (pH 7.4) 2.93

Charge Density (pH 7.0) 0.0274

GRAVY Index0.01

Hydrophobic Moment 0.53

Boman Index0.11

Instability Index17.09

Aliphatic Index 93.16

Aromaticity 0.0789

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5057.10

LogP -58.57

H-bond Donors 182.0

H-bond Acceptors 177.0

Rotatable Bonds 406.0

Heavy Atoms 864.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0314947 VERIFIED: NO

Provenance & Taxonomy

OrganismBucorvus abyssinicus (Northern ground-hornbill) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria