Peptide Database

Peptide NameL-Pro-WMR

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC106H171N33O32

DescriptionStandard

        EEEEAAAGWGLRRLLKYGKRS
    

Molecular Weight2419.69 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)0.84

Net Charge (pH 7.4) 0.66

Charge Density (pH 7.0) 0.0401

GRAVY Index-1.08

Hydrophobic Moment 0.93

Boman Index-0.29

Instability Index117.80

Aliphatic Index 70.00

Aromaticity 0.0952

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1088.51

LogP -9.64

H-bond Donors 40.0

H-bond Acceptors 33.0

Rotatable Bonds 84.0

Heavy Atoms 171.0

Ring Count 3.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419786 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Bio-Activity Profile

Function

Hemolytic

TargetCystic fibrosis bronchial epithelial cells CFBE41o- (IC50 at >300 microM, Cystic fibrosis bronchial epithelial cells CFBE41o- (IC50 at >300 microM

Activity41 μM

MethodHemolysis

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