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MYP_100187
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
38 amino acids
C180H274N60O50S6
Standard
Sequence
GFGCPWNRYQCHSHCRSIGRLGGYCAGSLRLTCTCYRS
Physicochemical Analysis
4270.86 Da
9.18
4.87
4.48
0.1282
-0.36
0.65
-0.08
55.24
43.68
0.1316
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1782.13
-22.66
73.0
63.0
133.0
296.0
9.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0330577 VERIFIED: YES
Provenance & Taxonomy
American oyster [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. hyicus NCTC 10350
16 μg/mL
MIC
PaperPurification of a novel arthropod defensin from the American oyster, Crassostrea virginica
RECORD: Rec_0341965 VERIFIED: YES
Provenance & Taxonomy
American oyster [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S-flexneri CMCC 51571
>64 μg/mL
MIC
PaperPurification of a novel arthropod defensin from the American oyster, Crassostrea virginica
RECORD: Rec_0366261 VERIFIED: YES
Provenance & Taxonomy
Crassostrea virginica [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
lactis
MEC
PaperPubMed PMID: 16297885 PMID16297885 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16297885/
RECORD: Rec_0379984 VERIFIED: YES
Provenance & Taxonomy
Crassostrea virginica [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Lactococcus lactis subsp. lactis
PMID16297885 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16297885/
RECORD: Rec_0400985 VERIFIED: YES
Provenance & Taxonomy
Crassostrea virginica [Animal]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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