Peptide Database

Peptide NameProtein S100-A8 (Calgranulin-A) (Migration inhibitory factor-related protein 8) (MRP-8) (p8) (S100 calcium-binding protein A8)

Function Ontology

Antimicrobial

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC453H705N125O140S3

DescriptionStandard

        MATELEKALSNVIEVYHNYSGIKGNHHALYRDDFRKMVTTECPQFVQNKNTESLFKELDVNSDNAINFEEFLVLVIRVGVAAHKDSHKE
    

Molecular Weight10238.39 Da

Isoelectric Point (pI)5.68

Net Charge (pH 7.0)-4.05

Net Charge (pH 7.4) -4.57

Charge Density (pH 7.0) -0.0455

GRAVY Index-0.46

Hydrophobic Moment 0.61

Boman Index-0.05

Instability Index40.20

Aliphatic Index 84.27

Aromaticity 0.0899

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4322.43

LogP -41.82

H-bond Donors 147.0

H-bond Acceptors 144.0

Rotatable Bonds 348.0

Heavy Atoms 721.0

Ring Count 14.0

Amide Bonds 98.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0000915 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyS-100

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antioxidant Autophagy-modulating Non-hemolytic

TargetNo Target Organism Found