Peptide Database

Peptide NameNatriuretic peptides B

Function Ontology

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC525H861N167O159S4

DescriptionStandard

        HPLGGRSPASEASEASEASGLWAVQELLGRLKDAVSELQAEQLALEPLHRSHSPAEAPEAGGTPRGVLAPHDSVLQALRRLRSPKMMHKSGCFGRRLDRIGSLSGLGCNVLRKY
    

Molecular Weight12184.74 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)3.20

Net Charge (pH 7.4) 2.69

Charge Density (pH 7.0) 0.0281

GRAVY Index-0.41

Hydrophobic Moment 0.78

Boman Index-0.07

Instability Index84.50

Aliphatic Index 85.70

Aromaticity 0.0263

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5191.97

LogP -59.88

H-bond Donors 184.0

H-bond Acceptors 171.0

Rotatable Bonds 405.0

Heavy Atoms 855.0

Ring Count 17.0

Amide Bonds 118.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0094559 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis familiaris [Animal]

FamilyNatriuretic peptide

Tax ID9615

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide92-108

Bio-Activity Profile

Function

Hormone Cardiovascular