Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length225 amino acids

Chemical FormulaC1138H1747N255O340S12

DescriptionStandard

        LCIHKIISMFFVIFCVLSTTLTAVMQIDDLAEVVYSLSGLLAVFQTFIDLDLKGIVFPAGNHTDSPYMAASFTIPDQSDSMLYLACSEYFFQSSSFAYYTAGAFNMTIAEEVKSGNSFVFSLLFFPSDLSYFNINTEIFSSTIPEVAKYSITPYLVMLKLMSSEIPTISLQQDSFTAEIQGSVEVLAILPDSTTQSLFTLTIAANTSISLNIFDQKLMGSLCLNR
    

Molecular Weight24825.33 Da

Isoelectric Point (pI)4.15

Net Charge (pH 7.0)-13.08

Net Charge (pH 7.4) -13.49

Charge Density (pH 7.0) -0.0581

GRAVY Index0.56

Hydrophobic Moment 0.55

Boman Index0.30

Instability Index46.42

Aliphatic Index 103.60

Aromaticity 0.1289

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13660.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056294 VERIFIED: NO

Provenance & Taxonomy

OrganismAgelaius phoeniceus (Red-winged blackbird) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria