‹ ›
MYP_100108
← PREVIOUS NEXT → BACK
Basic Information
NRC-13
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
23 amino acids
C125H210N34O29
Standard
Sequence
GWRTLLKKAEVKTVGKLALKHYL
Physicochemical Analysis
2653.22 Da
10.30
4.84
4.58
0.2106
-0.18
0.53
-0.02
14.33
118.70
0.0870
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1037.98
-4.92
38.0
35.0
92.0
188.0
4.0
22.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0038937 VERIFIED: YES
Provenance & Taxonomy
Hippoglossoides platessoides [Animal]
Pleurocidin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa Z61
1 μg/mL
MIC
PMID12878506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878506/
RECORD: Rec_0049294 VERIFIED: YES
Provenance & Taxonomy
Glyptocephalus cynoglossus L. [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
S. enterica serovar Typhimurium MS7953s
2 μg/mL
MIC
PaperA novel antimicrobial vermipeptide family from earthworm Eisenia fetida. Eur. J Soil Biol 2007; 43:S217-S134 Evidence URLhttps://camp3.bicnirrh.res.in/seqDisp.php?id=CAMPSQ2885
RECORD: Rec_0054923 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
Human erythrocytes
256 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/21729875/ PMID21729875 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21729875/
RECORD: Rec_0061060 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation
Amidation
Bio-Activity Profile
Antimicrobial
4T1
50 μM
Concentration response
PaperPleurocidin-family cationic antimicrobial peptides are cytolytic for breast carcinoma cells and prevent growth of tumor xenografts PMID22023734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22023734/
RECORD: Rec_0064258 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation
Amidation
Bio-Activity Profile
Antimicrobial
MDA-MB-468
50 μM
Concentration response
PaperPleurocidin-family cationic antimicrobial peptides are cytolytic for breast carcinoma cells and prevent growth of tumor xenografts PMID22023734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22023734/
FIRST PREV 1 2 3 4 ... 14 NEXT LAST
Showing 5 records on this page · Page 2 of 14