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MYP_100108
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Basic Information
NRC-13
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
23 amino acids
C125H210N34O29
Standard
Sequence
GWRTLLKKAEVKTVGKLALKHYL
Physicochemical Analysis
2653.22 Da
10.30
4.84
4.58
0.2106
-0.18
0.53
-0.02
14.33
118.70
0.0870
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1037.98
-4.92
38.0
35.0
92.0
188.0
4.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0384996 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation
Amidation
Bio-Activity Profile
Antimicrobial
SKBR-3
5 μM
Concentration response
PaperPleurocidin-family cationic antimicrobial peptides are cytolytic for breast carcinoma cells and prevent growth of tumor xenografts PMID22023734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22023734/
RECORD: Rec_0389054 VERIFIED: YES
Provenance & Taxonomy
Hippoglossoides platessoides [Animal]
Pleurocidin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa K799
4 μg/mL
MIC
PMID12878506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878506/
RECORD: Rec_0389953 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation
Amidation
Bio-Activity Profile
Antimicrobial
MCF-7-TX400
50 μM
Concentration response
PaperPleurocidin-family cationic antimicrobial peptides are cytolytic for breast carcinoma cells and prevent growth of tumor xenografts PMID22023734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22023734/
RECORD: Rec_0412736 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation
Amidation
Bio-Activity Profile
Antimicrobial
MDA-MB-468
10 μM
Concentration response
PaperPleurocidin-family cationic antimicrobial peptides are cytolytic for breast carcinoma cells and prevent growth of tumor xenografts PMID22023734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22023734/
RECORD: Rec_0418250 VERIFIED: YES
Provenance & Taxonomy
Hippoglossoides platessoides [Animal]
Pleurocidin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella enterica serovar typhimurium 14028s
8 μg/mL
MIC
PMID12878506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878506/
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