Peptide Database

Peptide NameNeurotoxin BmK-M10

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC303H468N84O94S8

DescriptionStandard

        VRDAYIAKPENCVYECGITQDCNKLCTENGAESGYCQWGGKYGNACWCIKLPDSVPIRVPGKCQ
    

Molecular Weight7047.98 Da

Isoelectric Point (pI)6.27

Net Charge (pH 7.0)-0.34

Net Charge (pH 7.4) -0.69

Charge Density (pH 7.0) -0.0053

GRAVY Index-0.42

Hydrophobic Moment 0.46

Boman Index-0.02

Instability Index34.67

Aliphatic Index 60.94

Aromaticity 0.0938

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2871.51

LogP -30.86

H-bond Donors 104.0

H-bond Acceptors 102.0

Rotatable Bonds 226.0

Heavy Atoms 489.0

Ring Count 12.0

Amide Bonds 70.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0425585 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilySodium channel inhibitor family

Tax ID34649; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-63; 16-36; 22-46; 26-48

Bio-Activity Profile

Function

Toxin Venom Sodium channel inhibitor family Pathogenesis-associated Host defense