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MYP_100091
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Basic Information
Brevinin-1Ba
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
24 amino acids
C128H202N28O26S3
Standard
Sequence
FLPFIAGMAAKFLPKIFCAISKKC
Physicochemical Analysis
2645.34 Da
9.70
3.74
3.50
0.1557
1.10
0.60
0.39
35.26
97.92
0.1667
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
839.35
-1.41
30.0
33.0
85.0
185.0
6.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0195948 VERIFIED: YES
Provenance & Taxonomy
Lithobates berlandieri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Non-hemolytic
Gram-positive bacteria
PMID10651828 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10651828/
RECORD: Rec_0208790 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 33.3%, E 0.0%, T 33.3%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0273267 VERIFIED: YES
Provenance & Taxonomy
Rana berlandieri [Animal]
Brevinin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
18-24
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
2.0 μM
MIC
PaperJ. Goraya et al. / Eur. J. Biochem. 267 (2000) 894-900. Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens PMID10651828 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10651828/
RECORD: Rec_0276093 VERIFIED: YES
Provenance & Taxonomy
Lithobates pipiens [Animal]
Brevinin
8404
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
2 μM
MIC
PaperPeptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens. PMID10651828 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10651828/
RECORD: Rec_0362233 VERIFIED: YES
Provenance & Taxonomy
Grande leopard [Animal]
Brevinin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial
PMID10651828 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10651828/
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