Peptide Database

Peptide NameCathelicidin antimicrobial peptide [Cleaved into: Antibacterial peptide FALL-39 (FALL-39 peptide antibiotic); Antibacterial peptide LL-37]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length170 amino acids

Chemical FormulaC850H1385N247O251S8

DescriptionStandard

        MKTQRDSPSLGRWSLVLLLLGLVMPLAIVAQVLSYQEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCMGTVTLNQARDSFDISCDKDNRRFALPGNFFRKAREKIGKEFKRIVQRIKDFLQHLVPRTEA
    

Molecular Weight19337.11 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)5.57

Net Charge (pH 7.4) 5.20

Charge Density (pH 7.0) 0.0328

GRAVY Index-0.45

Hydrophobic Moment 0.94

Boman Index-0.14

Instability Index43.88

Aliphatic Index 85.41

Aromaticity 0.0647

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8100.56

LogP -88.63

H-bond Donors 284.0

H-bond Acceptors 266.0

Rotatable Bonds 651.0

Heavy Atoms 1356.0

Ring Count 24.0

Amide Bonds 183.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0059526 VERIFIED: YES

Provenance & Taxonomy

OrganismNomascus concolor [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Antibiofilm Antifungal Anti-Candida Anti-Gram-negative Hemolytic

TargetEscherichia coli

RECORD: Rec_0121773 VERIFIED: YES