Peptide Database

Peptide NameTP 850

Function Ontology

Blood Coagulation

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC36H59N13O11

DescriptionStandard

        GPRPPAAGGA
    

Molecular Weight849.93 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.0760

GRAVY Index-0.51

Hydrophobic Moment 0.24

Boman Index0.11

Instability Index63.09

Aliphatic Index 30.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 360.75

LogP -5.50

H-bond Donors 11.0

H-bond Acceptors 12.0

Rotatable Bonds 20.0

Heavy Atoms 60.0

Ring Count 3.0

Amide Bonds 9.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0161329 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermNone

Other Mods4-aminobutyric acid (Aba)

Bio-Activity Profile

Function

Blood Coagulation

Targetdog and IC50=167μm for rabbit

Activity236 μM

MethodIC50

Half-LifeIntravenous injection,Blood sample of rabbit, in vivo; 240 s