Peptide Database

Peptide NameProtein S100-A8 (Calgranulin-A) (Chemotactic cytokine CP-10) (Leukocyte L1 complex light chain) (Migration inhibitory factor-related protein 8) (MRP-8) (p8) (Pro-inflammatory S100 cytokine) (S100 calcium-binding protein A8)

Function Ontology

Antimicrobial

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC456H705N123O141S4

DescriptionStandard

        MPSELEKALSNLIDVYHNYSNIQGNHHALYKNDFKKMVTTECPQFVQNINIENLFRELDINSDNAINFEEFLAMVIKVGVASHKDSHKE
    

Molecular Weight10294.47 Da

Isoelectric Point (pI)5.43

Net Charge (pH 7.0)-5.05

Net Charge (pH 7.4) -5.57

Charge Density (pH 7.0) -0.0567

GRAVY Index-0.47

Hydrophobic Moment 0.63

Boman Index-0.01

Instability Index58.50

Aliphatic Index 86.52

Aromaticity 0.0899

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4304.67

LogP -41.31

H-bond Donors 142.0

H-bond Acceptors 145.0

Rotatable Bonds 350.0

Heavy Atoms 724.0

Ring Count 15.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0371867 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyS-100

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antioxidant Autophagy-modulating Non-hemolytic

TargetNo Target Organism Found