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MYP_100014
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Basic Information
Pep1
Anticancer
Anticancer ▸ Anti-breast cancer
Anticancer ▸ Apoptosis induction
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV ▸ Anti-HSV-1
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Standard
22 amino acids
C123H200N40O26S3
Standard
Sequence
FKCRRWQWRMKKLGAPSITCVR
Physicochemical Analysis
2751.35 Da
11.57
6.74
6.50
0.3062
-0.66
0.57
-0.32
61.15
53.18
0.1364
11000.00
11125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1106.42
-8.13
44.0
36.0
91.0
192.0
6.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002963 VERIFIED: YES
Provenance & Taxonomy
Bovine lactoferrin [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 18425992 PMID18425992 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18425992/
RECORD: Rec_0151653 VERIFIED: YES
Provenance & Taxonomy
Bovine lactoferrin [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 18425992 PMID18425992 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18425992/
RECORD: Rec_0173941 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0198015 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 18.2%, T 36.4%, C 45.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Antimicrobial
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0204450 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Lactoferricin
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic Anti-HSV-1 Antiviral Anti-angiogenic
Herpes simplex virus 1
Cell proliferation assay
PaperBovine Lactoferricin Inhibits Basic Fibroblast Growth Factor- and Vascular Endothelial Growth Factor165-Induced Angiogenesis by Competing for Heparin-Like Binding Sites on Endothelial Cells | Mader, J. et al. | DOI: 10.2353/ajpath.2006.051229 Evidence URLhttps://www.uniprot.org/uniprotkb/P24627/entry
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