Peptide Database

Peptide NameSomatomedin c

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC334H518N94O99S7

DescriptionStandard

        GPETLCGAELVDALQFVCGDRGFYFNKPTGYGYGSSRRAPQTGIVDECCFRSCDLRRLMYCAPLKPAKSA
    

Molecular Weight7658.71 Da

Isoelectric Point (pI)8.30

Net Charge (pH 7.0)1.71

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0244

GRAVY Index-0.24

Hydrophobic Moment 0.47

Boman Index-0.02

Instability Index62.06

Aliphatic Index 60.00

Aromaticity 0.1143

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3089.63

LogP -33.08

H-bond Donors 114.0

H-bond Acceptors 108.0

Rotatable Bonds 244.0

Heavy Atoms 534.0

Ring Count 13.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0064757 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Endocrine

Targetnormal muscle homeostasis which is disrupted in fibromyalgia. Regression analysis shows that ~7 % low level of somatomedin c in case of fibromyalgia patients

MethodPeptide specific immunoassay

Half-LifeHuman serum sample, in vitro; 72000 s