Peptide Database

Peptide NameVenom peptide 1 (EpVP1) (VP1) (Eumenitin VP1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC302H490N76O83S

DescriptionStandard

        MRGTSFILFAVVVILGFLHANAEPLANPAPLANPDPLANADPLADPEAINLKGLIKKVASLLT
    

Molecular Weight6545.65 Da

Isoelectric Point (pI)5.50

Net Charge (pH 7.0)-1.41

Net Charge (pH 7.4) -1.68

Charge Density (pH 7.0) -0.0223

GRAVY Index0.59

Hydrophobic Moment 0.57

Boman Index0.30

Instability Index13.80

Aliphatic Index 128.73

Aromaticity 0.0476

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2457.50

LogP -18.20

H-bond Donors 78.0

H-bond Acceptors 84.0

Rotatable Bonds 205.0

Heavy Atoms 462.0

Ring Count 11.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0042197 VERIFIED: YES

Provenance & Taxonomy

OrganismEumenes pomiformis [Animal]

FamilyMCD; Eumenitin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetGram-negative and Gram-positive bacteria