Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC543H877N147O165S2

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIHVTAVELPSASISLLPASGIKLVIGNASLAIDMDWNIRTWIFKDSGRGTVHISKVFVTAIFSTPLDNTGPTSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12168.79 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)2.22

Net Charge (pH 7.4) 1.97

Charge Density (pH 7.0) 0.0194

GRAVY Index0.10

Hydrophobic Moment 0.54

Boman Index0.14

Instability Index19.85

Aliphatic Index 101.75

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4970.05

LogP -54.99

H-bond Donors 177.0

H-bond Acceptors 172.0

Rotatable Bonds 401.0

Heavy Atoms 857.0

Ring Count 17.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0284753 VERIFIED: NO

Provenance & Taxonomy

OrganismMelanocharis versteri [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria