Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length205 amino acids

Chemical FormulaC1029H1595N231O313S11

DescriptionStandard

        KIISVFLVILCVLSTTLTAVMQIDDLVEVDYSLSSLPAVFQPFIDLDLKGVVFPAGNSTDCPYVAASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTIAEETCSYFNINTEIFSSIIPEVAKYSVTPYPVMLKLMSTEIPIISLQQDSFTAEIQGSMEVLAILPDSTTRSLFTLSIAANTSISLNIFDQKLMGSLCLNR
    

Molecular Weight22562.75 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-13.26

Net Charge (pH 7.4) -13.56

Charge Density (pH 7.0) -0.0647

GRAVY Index0.52

Hydrophobic Moment 0.55

Boman Index0.28

Instability Index43.19

Aliphatic Index 105.12

Aromaticity 0.1171

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13660.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0147083 VERIFIED: NO

Provenance & Taxonomy

OrganismPromerops cafer [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria