Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length108 amino acids

Chemical FormulaC545H860N150O153S3

DescriptionStandard

        QIPQQFPFQLRTKSMEVFSPQLQELYPDQPMELHLWARRQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPELG
    

Molecular Weight12057.77 Da

Isoelectric Point (pI)7.03

Net Charge (pH 7.0)0.03

Net Charge (pH 7.4) -0.36

Charge Density (pH 7.0) 0.0003

GRAVY Index-0.15

Hydrophobic Moment 0.46

Boman Index0.06

Instability Index54.59

Aliphatic Index 93.89

Aromaticity 0.0741

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4794.71

LogP -43.84

H-bond Donors 160.0

H-bond Acceptors 159.0

Rotatable Bonds 381.0

Heavy Atoms 851.0

Ring Count 24.0

Amide Bonds 119.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0419487 VERIFIED: NO

Provenance & Taxonomy

OrganismMystacornis crossleyi [Plant]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria