Peptide Database

Peptide NameMotilin-associated peptide

Function Ontology

Gastrointestinal bioactivity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC383H609N119O127S4

DescriptionStandard

        SLSVQQRSDAAAAPRPAEPTLEEENGRMQLTAPVEIGMRMNSRQLEKYRAALEAAERAVHPDAPSRPCWPAGGESGWSGEPSPT
    

Molecular Weight9040.91 Da

Isoelectric Point (pI)5.07

Net Charge (pH 7.0)-3.43

Net Charge (pH 7.4) -3.73

Charge Density (pH 7.0) -0.0409

GRAVY Index-0.81

Hydrophobic Moment 0.65

Boman Index-0.14

Instability Index64.70

Aliphatic Index 53.69

Aromaticity 0.0357

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3921.10

LogP -48.73

H-bond Donors 134.0

H-bond Acceptors 129.0

Rotatable Bonds 287.0

Heavy Atoms 633.0

Ring Count 16.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010067 VERIFIED: YES

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyMotilin-associated peptide

Tax ID9986

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Myotropic

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0287831 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyMotilin

Tax ID9986

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Gastrointestinal

RECORD: Rec_0296852 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/