Peptide Database

Peptide NameMacromomycin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length148 amino acids

Chemical FormulaC642H1039N175O214S3

DescriptionStandard

        MTVKNKLGLATRITAATAVAAGLALAVQPSALAAATAPVVSVSPASDLTDGQQVTVTATGLTPNTVFHLGHCAFVEPEKYGCDATTAKDVVSDASGKVNTTITVHSSFEAVVTSDGAVWGTVDAKKTQTQVGLGSDAGEGGGQPVTFK
    

Molecular Weight14729.36 Da

Isoelectric Point (pI)5.44

Net Charge (pH 7.0)-3.25

Net Charge (pH 7.4) -3.67

Charge Density (pH 7.0) -0.0219

GRAVY Index0.19

Hydrophobic Moment 0.44

Boman Index0.18

Instability Index18.79

Aliphatic Index 83.72

Aromaticity 0.0405

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6142.94

LogP -80.90

H-bond Donors 213.0

H-bond Acceptors 217.0

Rotatable Bonds 473.0

Heavy Atoms 1034.0

Ring Count 16.0

Amide Bonds 156.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0120121 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptomyces sp. ICN441 [Bacterium]

FamilyNeocarzinostatin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal

RECORD: Rec_0372131 VERIFIED: NO