MYP_099900
Magainin-2 [G3K,S8I,A9I,K10W,G13I]
Antimicrobial
Antimicrobial
▸
Antibacterial
Antiparasitic
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Anti-Leishmania
▸
Antileishmanial
Antiparasitic
▸
General antiparasitic
▸
Antiparasitic
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Standard
23 amino acids
C133H207N31O28S
Standard
GIKKFLHIIWKFIKAFVGEIMNS
2720.32 Da
10.00
2.85
2.59
0.1237
0.62
0.74
0.33
19.00
118.70
0.1739
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
952.69
-1.30
33.0
33.0
93.0
193.0
6.0
23.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0210674
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
2.9 μM
Hemolysis
RECORD: Rec_0210828
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 43.5%, E 0.0%, T 47.8%, C 8.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiparasitic
Antimicrobial
Antileishmanial
RECORD: Rec_0230916
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
MG-H1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Antiparasitic
Antileishmanial
Leishmania donovani MHOM/SD/00/1S-2D (promastigote)
5.0 μM
LD50; MTT assay
RECORD: Rec_0426619
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Escherichia coli ATCC 25922
16 μM
MIC