Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC216H349N57O68S3

DescriptionStandard

        MAKQQMNLVEIEAMNSLQELTLEELDNVLGAGGGVIHFIQTKQW
    

Molecular Weight4928.62 Da

Isoelectric Point (pI)4.41

Net Charge (pH 7.0)-4.40

Net Charge (pH 7.4) -4.68

Charge Density (pH 7.0) -0.1000

GRAVY Index-0.04

Hydrophobic Moment 0.40

Boman Index0.15

Instability Index65.39

Aliphatic Index 106.36

Aromaticity 0.0455

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2040.34

LogP -17.83

H-bond Donors 66.0

H-bond Acceptors 68.0

Rotatable Bonds 172.0

Heavy Atoms 344.0

Ring Count 4.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0157095 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus mitis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria