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MYP_099808
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Basic Information
Ocellatin-1I
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
21 amino acids
C96H168N26O27
Standard
Sequence
GLLDLLKGAGKGLLTHLASQI
Physicochemical Analysis
2118.52 Da
8.60
0.85
0.59
0.0403
0.65
0.57
0.31
-1.52
158.10
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
846.89
-6.63
29.0
29.0
74.0
149.0
1.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0191061 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus insularum [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 35218
62.5 μM
MIC
PMID33092132 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33092132/
RECORD: Rec_0256405 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus insularum [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 35218
62.5 μM
MIC
PaperPeptidomic Analysis of Skin Secretions of the Caribbean Frogs Leptodactylus insularum and Leptodactylus nesiotus (Leptodactylidae) Identifies an Ocellatin with Broad Spectrum Antimicrobial Activity
RECORD: Rec_0311751 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus insularum [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
reference strains of Klebsiella pneumoniae ATCC 49472
125 μM
MIC
PaperPeptidomic Analysis of Skin Secretions of the Caribbean Frogs Leptodactylus insularum and Leptodactylus nesiotus (Leptodactylidae) Identifies an Ocellatin with Broad Spectrum Antimicrobial Activity
RECORD: Rec_0315692 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus insularum [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Mouse erythrocytes
>250 μg/mL
HC50
PMID33092132 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33092132/
RECORD: Rec_0323275 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus insularum [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
E.faecium ATCC 19434
250 μM
MIC
PaperPeptidomic Analysis of Skin Secretions of the Caribbean Frogs Leptodactylus insularum and Leptodactylus nesiotus (Leptodactylidae) Identifies an Ocellatin with Broad Spectrum Antimicrobial Activity
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