Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC457H722N110O122S7

DescriptionStandard

        PFLFPFKIIFIFSLLKCFGNIKGYCRKKCRMGEIYEIACTNGKLCCVNEEENKAYQEVAKPPQPSTKPDLKLDYVILPTVTVNTIPL
    

Molecular Weight9933.74 Da

Isoelectric Point (pI)8.82

Net Charge (pH 7.0)3.90

Net Charge (pH 7.4) 3.73

Charge Density (pH 7.0) 0.0449

GRAVY Index0.01

Hydrophobic Moment 0.56

Boman Index0.09

Instability Index38.09

Aliphatic Index 91.84

Aromaticity 0.1149

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3696.96

LogP -25.01

H-bond Donors 129.0

H-bond Acceptors 133.0

Rotatable Bonds 325.0

Heavy Atoms 696.0

Ring Count 18.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0310580 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence